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Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen , which causes it to polymerize .
A Hollenhorst plaque (also known as a retinal cholesterol embolus) is a cholesterol embolus that is seen in a blood vessel of the retina.It is usually found when a physician performs ophthalmoscopy, during which a plaque will appear as a small, bright crystal that is refractile (reflects the light from the ophthalmoscope) and yellow. [1]
Heart attack. A heart attack results from a sudden plaque rupture and formation of a thrombus (blood clot) that completely blocks blood flow to a portion of the heart, leading to tissue death . CAD can also result in heart failure or arrhythmias. Heart failure is caused by chronic oxygen deprivation due to reduced blood flow, which weakens the ...
They have layers, with lighter layers of platelets and fibrin, and darker layers of red blood cells. They are more present on thrombi formed with faster blood flow, more so on thrombi from the heart and aorta. They are only seen on thrombi formed before death. They are named after German–Swiss pathologist Friedrich Wilhelm Zahn.
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).
Fibrin scaffold use is helpful in repairing injuries to the urinary tract, [3] liver [4] lung, [5] spleen, [6] kidney, [7] and heart. [8] In biomedical research, fibrin scaffolds have been used to fill bone cavities, repair neurons, heart valves, [ 9 ] vascular grafts [ 10 ] and the surface of the eye.
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
A myocardial infarction, also known as a heart attack, often result in the formation of fibrosis. [2] A myocardial infarction is an ischemic event, or a restriction of blood flow to body tissue, such as by atherothrombosis. [4] Without blood flow to the myocardium, it is deprived of oxygen, causing tissue death and irreversible damage. [5]