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Systems biology is a branch of biological data visualization dedicated to analyzing and modeling complex biological systems. Popular computational models used in systems biology include process calculi , such as stochastic π-calculus , and constraint-based reconstruction and analysis (COBRA), a paradigm that considers physical, enzymatic, and ...
In the genomic branch of bioinformatics, homology is used to predict the function of a gene: if the sequence of gene A, whose function is known, is homologous to the sequence of gene B, whose function is unknown, one could infer that B may share A's function. In structural bioinformatics, homology is used to determine which parts of a protein ...
Biological data has also been difficult to define, as bioinformatics is a wide-encompassing field. Further, the question of what constitutes as being a living organism has been contentious, as "alive" represents a nebulous term that encompasses molecular evolution, biological modeling, biophysics, and systems biology.
Bioinformatics and computational biology are interdisciplinary fields of research, development and application of algorithms, computational and statistical methods for management and analysis of biological data, and for solving basic biological problems.
Structural bioinformatics is the branch of bioinformatics that is related to the analysis and prediction of the three-dimensional structure of biological macromolecules such as proteins, RNA, and DNA. It deals with generalizations about macromolecular 3D structures such as comparisons of overall folds and local motifs, principles of molecular ...
While each field is distinct, there may be significant overlap at their interface, [1] so much so that to many, bioinformatics and computational biology are terms that are used interchangeably. The terms computational biology and evolutionary computation have a similar name, but are not to be confused. Unlike computational biology, evolutionary ...
1.2 Charts and diagrams. ... This list of research methods in biology is an index to articles about research methodologies used in various branches of biology.
A dendrogram is a diagram representing a tree. This diagrammatic representation is frequently used in different contexts: in hierarchical clustering, it illustrates the arrangement of the clusters produced by the corresponding analyses. [4] in computational biology, it shows the clustering of genes or samples, sometimes in the margins of ...