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Amitriptyline is the English and French generic name of the drug and its INN Tooltip International Nonproprietary Name, BAN Tooltip British Approved Name, and DCF Tooltip Dénomination Commune Française, while amitriptyline hydrochloride is its USAN Tooltip United States Adopted Name, USP Tooltip United States Pharmacopeia, BANM Tooltip ...
Amitriptylinoxide (brand names Amioxid, Ambivalon, Equilibrin), or amitriptyline N-oxide, is a tricyclic antidepressant (TCA) which was introduced in Europe in the 1970s for the treatment of depression. [1] Amitriptylinoxide is both an analogue and metabolite of amitriptyline, and has similar effects as well as equivalent efficacy as an ...
Previous systematic reviews and meta-analyses had not comprehensively assessed TCAs in the same fashion, with the largest including only two TCAs (amitriptyline and clomipramine) and only 36 trials. [11] [12] A total of 103 short-term clinical trials with 10,590 participants employing 12 different TCAs (and TeCAs) were included. [11]
Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo; Viibryd – an antidepressant of the serotonin modulator and stimulators class; Vivactil (protriptyline) an antidepressant also used in the treatment of nerve pain
Minitran is a commercial psychiatric drug used as a tranquilliser and antidepressant. It is manufactured in Greece by Adelco S.A. and sold in form of yellow-coloured sugar-coated tablets. [1] It contains Amitriptyline hydrochloride and Perphenazine. It is sold in the following forms:
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Amitriptyline Nortriptyline (Amitriptyline's active metabolite) Perphenazine Notes SERT: 3.13: 16.5? It is this and its NET-inhibiting action is believed to give amitriptyline its antidepressant action. NET: 22.4: 4.37? See above. DAT: 5380: 3100? 5-HT 1A: 450: 294: 421: Binding for human brain receptors had to be substituted in amitriptyline ...
The TCAs such as imipramine and amitriptyline typically prevent the reuptake of serotonin or norepinephine. It is the histaminiergic (H 1 ), muscarinic acetylcholinergic (M 1 ), and alpha adrenergic (α 1 ) blockade that is responsible for the side-effects of TCAs.