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Insufficient data exist, [25] but it is estimated to have caused the death of 34,000 children under the age of five in 2013, and 40,000 deaths in people over five years of age. [16] Shigella also causes about 580,000 cases annually among travelers and military personnel from industrialized countries. [26]
The ACIP was established in March 1964 by the US Surgeon General to assist in the prevention and control of communicable diseases, [2] it recommends licensed new vaccines to be incorporated into the routine immunization schedule, recommends vaccine formulations, and reviews older vaccines to consider revising its recommendations.
Hence, Shigella cells may cause dysentery. In rare cases, young children may have seizures. Symptoms can take as long as a week to appear, but most often begin two to four days after ingestion. Symptoms usually last for several days, but can last for weeks. Shigella is implicated as one of the pathogenic causes of reactive arthritis worldwide. [21]
For example, Shigella is a longstanding World Health Organization (WHO) target for vaccine development, and sharp declines in age-specific diarrhea/dysentery attack rates for this pathogen indicate that natural immunity does develop following exposure; thus, vaccination to prevent this disease should be feasible. The development of vaccines ...
But progress has been slow: Since vaccines became available to that age group, the L.A. Times vaccine tracker indicates, only 22% of eligible children have received at least one dose in California ...
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Since 1990, when the vaccine was introduced as a routine vaccination in children, rates of acute Hepatitis B has decreased in the United States by 82%. This vaccine is given as a series of shots, the first dose is given at birth, the second between 1 and 2 months, and the third, and possibly fourth, between 6 and 18 months.
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