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Signs and symptoms of ototoxicity include tinnitus, hearing loss, dizziness and nausea and/or vomiting. [3] The diagnosis of medicine-induced ototoxicity is challenging as it usually shows only mild symptoms in early stages. Thus, prospective ototoxicity monitoring would be required when patients are using ototoxic medications. [1]
At high doses, quinine, aspirin and other salicylates may also cause high-pitch tinnitus and hearing loss in both ears, typically reversible upon discontinuation of the drug. [20] Erectile dysfunction medications may have the potential to cause hearing loss. [36] However the link between erectile dysfunction medications and hearing loss remains ...
Tinnitus (ringing in the ears) Migraine; Stevens–Johnson syndrome/toxic epidermal necrolysis (potentially fatal skin reactions) Motorial weakness; Creatinine increase; Elevated liver enzymes; Hepatitis (liver swelling) Stomatitis (mouth swelling) Liver failure; Pulmonary oedema (fluid in the lungs) Gastrointestinal bleeding; Pulmonary embolism
Key Takeaways: Tinnitus is a symptom with numerous causes. Vascular causes, such as high blood pressure, can lead to tinnitus for some individuals.
The symptoms include depression, anxiety, psychosis, paranoia, severe insomnia, paresthesia, tinnitus, hypersensitivity to light (photophobia) and sound (hyperacusis), tremors, status epilepticus, suicidal thoughts and suicide attempt. Fluoroquinolone antibiotics should be contraindicated in patients who are dependent on or in benzodiazepine ...
The second is tailored music therapy, notched at the tinnitus frequency, which may affect lateral inhibition of the notched neural region, suppressing tinnitus. [ 108 ] [ 109 ] There is some tentative evidence supporting tinnitus retraining therapy , which aims to reduce tinnitus-related neuronal activity.
tinnitus, ringing, buzzing, hissing or other sounds in the ear when no external sound is present vertigo and disequilibrium tympanophonia , also known as autophonia, abnormal hearing of one's own voice and respiratory sounds, usually as a result of a patulous (a constantly open) eustachian tube or dehiscent superior semicircular canals
These include both symptoms typical of opioid withdrawal and those associated with serotonin–norepinephrine reuptake inhibitor (SNRI) withdrawal; symptoms include numbness, tingling, paresthesia, and tinnitus. [40] Psychiatric symptoms may include hallucinations, paranoia, extreme anxiety, panic attacks, and confusion. [41]
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