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In pathology, pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. [1] The word comes from Ancient Greek πάθος (pathos) 'suffering, disease' and γένεσις (genesis) 'creation'.
Etiology (/ ˌ iː t i ˈ ɒ l ə dʒ i /; alternatively spelled aetiology or ætiology) is the study of causation or origination. The word is derived from the Greek word αἰτιολογία ( aitiología ), meaning "giving a reason for" (from αἰτία ( aitía ) 'cause' and -λογία ( -logía ) 'study of'). [ 1 ]
Cause, also known as etiology (/ iː t i ˈ ɒ l ə dʒ i /) and aetiology, is the reason or origination of something. [ 1 ] The word etiology is derived from the Greek αἰτιολογία , aitiologia , "giving a reason for" ( αἰτία , aitia , "cause"; and -λογία , -logia ).
The origins of pathophysiology as a distinct field date back to the late 18th century. The first known lectures on the subject were delivered by Professor August Friedrich Hecker at the University of Erfurt in 1790, and in 1791, he published the first textbook on pathophysiology, Grundriss der Physiologia pathologica, [2] spanning 770 pages. [3]
Autopsy (1890) by Enrique Simonet.. The natural history of disease is the course a disease takes in individual people from its pathological onset ("inception") until its resolution (either through complete recovery or eventual death). [1]
Viral pathogenesis is the study of the process and mechanisms by which viruses cause diseases in their target hosts, often at the cellular or molecular level. It is a specialized field of study in virology. [1] Pathogenesis is a qualitative description of the process by which an initial infection causes disease. [2]
Advances in medical science improve the understanding of causes of diseases and the classification of diseases; thus, regarding any particular condition or disease, as more root causes are discovered and as events that seemed spontaneous have their origins revealed, the percentage of cases designated as idiopathic will decrease.
More modern concepts in microbial pathogenesis cannot be examined using Koch's postulates, including viruses (which are obligate intracellular parasites) and asymptomatic carriers. They have largely been supplanted by other criteria such as the Bradford Hill criteria for infectious disease causality in modern public health and the Molecular ...