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The design for a medical study in 1743 that was never carried out may have inspired James Lind’s groundbreaking clinical trial that determined the treatment for scurvy. A 1747 study found the ...
The condition is associated with sailors who weren't eating fruit and vegetables — but it's more common than you'd think.
Scurvy is a deficiency disease (state of malnutrition) resulting from a lack of vitamin C (ascorbic acid). [1] Early symptoms of deficiency include weakness, fatigue, and sore arms and legs. [1] [2] Without treatment, decreased red blood cells, gum disease, changes to hair, and bleeding from the skin may occur.
Vitamin C is an essential nutrient used in the production of collagen and other biomolecules, and for the prevention of scurvy. [6] It is also an antioxidant , which has led to its endorsement by some researchers as a complementary therapy for improving quality of life . [ 7 ]
James Lind FRSE FRCPE (4 October 1716 – 13 July 1794) was a Scottish physician. He was a pioneer of naval hygiene in the Royal Navy.By conducting one of the first ever clinical trials, [1] [2] [3] he developed the theory that citrus fruits cured scurvy.
A 2015 (updated in 2022) Cochrane review of topical clonidine for the treatment of diabetic neuropathy included two studies of 8 and 12 weeks in length; both of which compared topical clonidine to placebo and both of which were funded by the same drug manufacturer. The review found that topical clonidine may provide some benefit versus placebo.
On at least three episodes Oz promoted colloidal silver as a treatment for cold symptoms, wounds, viruses, and bacteria, but there is no evidence at all to support any medical uses of it. [26] Despite Oz's recommendations, colloidal silver does not treat or prevent any disease or condition, and it is not proven safe to consume. [27]
In 1999, Johnson & Johnson had signed a contract with a company called Excerpta Medica. Its specialty was medical marketing. Its sub-specialty was producing ghostwritten, data-filled studies on the efficacy and safety of a client’s drugs, finding the right academic scholars to be listed as the authors and then placing the articles in prestigious academic journals.