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  2. Vitamin C megadosage - Wikipedia

    en.wikipedia.org/wiki/Vitamin_C_megadosage

    There is a strong advocacy movement for very high doses of vitamin C, yet there is an absence of large-scale, formal trials in the 10 to 200+ grams per day range. The single repeatable side effect of oral megadose vitamin C is a mild laxative effect if the practitioner attempts to consume too much too quickly.

  3. Megavitamin therapy - Wikipedia

    en.wikipedia.org/wiki/Megavitamin_therapy

    The US Recommended Dietary Allowance for vitamin C for adult women is 76 mg/day and for adult men 90 mg/day. Although Linus Pauling was known for highly respectable research in chemistry and biochemistry, he was also known for promoting the consumption of vitamin C in large doses. [ 25 ]

  4. Medicare now negotiating price of drug that costs $7,100 in ...

    www.aol.com/medicare-now-negotiating-price-drug...

    The annual list price of Bristol Myers Squibb’s Eliquis, a blood thinner that reduces the risk of stroke, is $7,100 in the US. But in Japan, it’s $940; in Canada, it’s $900; in Germany, it ...

  5. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    [8] [9] [10] It is used as an alternative to warfarin to prevent blood clots following hip or knee replacement and in those with a history of prior clots [8] [10] and does not require monitoring by blood tests [8] or dietary restrictions. [11] It is taken by mouth. [8] Common side effects include bleeding and nausea.

  6. Intravenous ascorbic acid - Wikipedia

    en.wikipedia.org/wiki/Intravenous_ascorbic_acid

    [10] [11] A systematic review of trials in 2021 found that the claimed benefits of the protocol could not be confirmed. [12] People in sepsis may have micronutrient deficiencies, including low levels of vitamin C. [13] Reviews mention that an intake of 3.0 g/day via intravenous administration may needed to maintain normal plasma concentrations.

  7. This popular vitamin C serum is on sale for just $10: '60 is ...

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    Eva Naturals Vitamin C Serum $10 $15 Save $5 This anti-aging hero is loaded with antioxidants and hyaluronic acid, helping to boost collagen production and reduce fine lines and wrinkles.

  8. Vitamin C - Wikipedia

    en.wikipedia.org/wiki/Vitamin_C

    Vitamin C megadosage is a term describing the consumption or injection of vitamin C in doses comparable to or higher than the amounts produced by the livers of mammals which are able to synthesize vitamin C. An argument for this, although not the actual term, was described in 1970 in an article by Linus Pauling. Briefly, his position was that ...

  9. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    Classically, for clinical indications of an approved drug, TI refers to the ratio of the dose of the drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD 50) to the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of ...

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