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Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infection [1] caused by Dabie bandavirus also known as the SFTS virus, first reported between late March and mid-July 2009 in rural areas of Hubei and Henan provinces in Central China.
The clinical condition it caused is known as severe fever with thrombocytopenia syndrome (SFTS). [2] SFTS is an emerging infectious disease that was first described in northeast and central China 2009 and now has also been discovered in Japan, South Korea, Vietnam and Taiwan in 2015.
This characteristic is shared by two related syndromes, hemolytic-uremic syndrome (HUS) and atypical hemolytic uremic syndrome (aHUS). [4] Consequently, differential diagnosis of these TMA diseases is essential. Both TTP and HUS are characterized by fever, anemia, thrombocytopenia, renal failure, and neurological symptoms. Generally, TTP has ...
The severity of thrombocytopenia may be correlated with pathogen type; some research indicates that the most severe cases are related to fungal or Gram-negative bacterial infection. [37] The pathogen may be transmitted during [ 39 ] or before birth, by breast feeding , [ 40 ] [ 41 ] [ 42 ] or during transfusion. [ 43 ]
Other causes of thrombocytopenia which may occur in pregnancy, such as drug induced thrombocytopenia, hereditary thrombocytopenia and pseudothrombocytopenia should also be ruled out. [63] ITP can be difficult to distinguish from gestational thrombocytopenia (which is by far the most common cause of thrombocytopenia in pregnancy). Unlike ITP ...
Purpura fulminans may also lead to severe large vessel venous thrombosis if untreated in its early stages. [2] Purpura fulminans secondary to severe infection is self-limiting. [2] In cases of homozygous protein C deficiency, episodes of purpura fulminans and other thrombotic events are recurrent. [4]
In 2022 — the most recent year for which mortality data is available — a total of 941,652 people died of heart disease-related condition
Low risk MDS (which is associated with favorable genetic variants, decreased myeloblastic cells [less than 5% blasts], less severe anemia, thrombocytopenia, or neutropenia or lower International Prognostic Scoring System scores) is associated with a life expectancy of 3–10 years. Whereas high risk MDS is associated with a life expectancy of ...
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