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  2. Chirality - Wikipedia

    en.wikipedia.org/wiki/Chirality

    Also, for artificial compounds, including medicines, in case of chiral drugs, the two enantiomers sometimes show remarkable difference in effect of their biological actions. [29] Darvon ( dextropropoxyphene ) is a painkiller, whereas its enantiomer, Novrad ( levopropoxyphene ) is an anti-cough agent.

  3. Chirality (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Chirality_(chemistry)

    A chiral molecule or ion exists in two stereoisomers that are mirror images of each other, [5] called enantiomers; they are often distinguished as either "right-handed" or "left-handed" by their absolute configuration or some other criterion. The two enantiomers have the same chemical properties, except when reacting with other chiral compounds.

  4. Chiral drugs - Wikipedia

    en.wikipedia.org/wiki/Chiral_drugs

    Louis Pasteur - pioneering stereochemist. Chirality can be traced back to 1812, when physicist Jean-Baptiste Biot found out about a phenomenon called "optical activity." [10] Louis Pasteur, a famous student of Biot's, made a series of observations that led him to suggest that the optical activity of some substances is caused by their molecular asymmetry, which makes nonsuperimposable mirror ...

  5. Chiral analysis - Wikipedia

    en.wikipedia.org/wiki/Chiral_analysis

    For chiral examination there is a need to have the right chiral environment. This could be provided as a plane polarized light, an additional chiral compound or by exploiting the inborn chirality of nature. The chiral analytical strategies incorporate physical, biological, and separation science techniques.

  6. Planar chirality - Wikipedia

    en.wikipedia.org/wiki/Planar_chirality

    A planar chiral derivative of ferrocene, used for kinetic resolution of some racemic secondary alcohols [1]. This term is used in chemistry contexts, [2] e.g., for a chiral molecule lacking an asymmetric carbon atom, but possessing two non-coplanar rings that are each dissymmetric and which cannot easily rotate about the chemical bond connecting them: 2,2'-dimethylbiphenyl is perhaps the ...

  7. Chiral resolution - Wikipedia

    en.wikipedia.org/wiki/Chiral_resolution

    Chiral resolution, or enantiomeric resolution, [1] is a process in stereochemistry for the separation of racemic mixture into their enantiomers. [2] It is an important tool in the production of optically active compounds, including drugs . [ 3 ]

  8. Chiral inversion - Wikipedia

    en.wikipedia.org/wiki/Chiral_inversion

    Chiral inversion is the process of conversion of one enantiomer of a chiral molecule to its mirror-image version with no other change in the molecule. [1] [2] [3] [4]Chiral inversion happens depending on various factors (viz. biological-, solvent-, light-, temperature- induced, etc.) and the energy barrier energy barrier associated with the stereogenic element present in the chiral molecule. 2 ...

  9. Axial chirality - Wikipedia

    en.wikipedia.org/wiki/Axial_chirality

    Two types of molecules having axial chirality: allenes (left) and binaryl atropisomers (right) In chemistry, axial chirality is a special case of chirality in which a molecule contains two pairs of chemical groups in a non-planar arrangement about an axis of chirality so that the molecule is not superposable on its mirror image.

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