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SCCmec, or staphylococcal cassette chromosome mec, is a mobile genetic element of Staphylococcus bacterial species. This genetic sequence includes the mecA gene coding for resistance to the antibiotic methicillin and is the only known way for Staphylococcus strains to spread the gene in the wild by horizontal gene transfer. [1]
The mecA gene, which confers resistance to a number of antibiotics, is always present in MRSA and usually absent in MSSA; however, in some instances, the mecA gene is present in MSSA but is not expressed. Polymerase chain reaction (PCR) testing is the most precise method for identifying MRSA strains. Specialized culture media have been ...
Staphylococcus pseudintermedius is becoming a threat due to its heterogeneous qualities [35] and multi-drug resistance phenotype. [2] [34] Methicillin-resistant S. pseudintermedius (MRSP) has five major clonal complex (CC) lineages, [2] each with their own unique traits regarding genetic diversity, geographical distribution and antimicrobial ...
Meca or MECA may refer to: Biology. mecA, responsible for methicillin resistance in MRSA; Meca, a snout moth genus in the subfamily Pyralinae; Places Meca ...
It also served a purpose in the laboratory to determine the antibiotic sensitivity of Staphylococcus aureus to other penicillins facing β-lactam resistance; this role has now been passed on to other penicillins, namely cloxacillin, as well as genetic testing for the presence of mecA gene by PCR. [citation needed]
(This diagram is modeled specifically on the way some strains of Staphylococcus aureus have evolved to resist the beta-lactam antibiotic methicillin by expressing the mecA gene.) 1- Both enzymes are structurally similar, but differ in the kind of substances they will allow in their active sites.
Behavioral epigenetics is the field of study examining the role of epigenetics in shaping animal and human behavior. [1] It seeks to explain how nurture shapes nature, [2] where nature refers to biological heredity [3] and nurture refers to virtually everything that occurs during the life-span (e.g., social-experience, diet and nutrition, and exposure to toxins). [4]
Although the term resistance as it is known today in psychotherapy is largely associated with Sigmund Freud, the idea that some patients "cling to their disease" [3] was a popular one in medicine in the nineteenth century, and referred to patients whose maladies were presumed to persist due to the secondary gains of social, physical, and financial benefits associated with illness. [4]