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Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. [1] It is a diastereomer of antimalarial agent quinine, [2] originally derived from the bark of the cinchona tree. The drug causes increased action potential duration, as well as a prolonged QT interval. As of 2019, its IV formulation is no longer being ...
Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia. Many attempts have been made to classify antiarrhythmic agents.
It may be used in pregnancy, but has not been well studied in this population. [3] [4] Use is not recommended in those with structural heart disease or ischemic heart disease. [1] Flecainide is a class Ic antiarrhythmic agent. [1] It works by decreasing the entry of sodium in heart cells, causing prolongation of the cardiac action potential. [1]
Lidocaine is often given intravenously as an antiarrhythmic agent in critical cardiac-care situations. [44] Treatment with intravenous lipid emulsions (used for parenteral feeding) to reverse the effects of local anaesthetic toxicity is becoming more common. [45] [46]
1 Antiarrhythmic agents. 2 ACE inhibitors. 3 Alpha blockers. ... The following are medications commonly prescribed cardiac pharmaceutical agents. The specificity of ...
QTc Bazett interval ≥500 ms, [3] or use with drugs or herbal supplements that prolong QT interval or increase risk of torsades de points (Class I or III antiarrhythmic agents, phenothiazines, tricyclic antidepressants, certain oral macrolides, ephedra). [citation needed] Pregnancy and nursing mothers [3] Hypersensitivity to dronedarone [3]
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.
Mexiletine (sold under the brand names Mexitil and Namuscla) is a medication used to treat abnormal heart rhythms, chronic pain, and some causes of muscle stiffness. Common side effects include abdominal pain, chest discomfort, drowsiness, headache, and nausea.
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