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Histologic image showing a section of epidermis. Stratum spinosum labeled slightly below center. The stratum spinosum (or spinous layer/prickle cell layer) [1] is a layer of the epidermis found between the stratum granulosum and stratum basale. [2] This layer is composed of polyhedral keratinocytes. [3] [4] These are joined with desmosomes. [3]
The stratum granulosum (or granular layer) is a thin layer of cells in the epidermis lying above the stratum spinosum and below the stratum corneum (stratum lucidum on the soles and palms). [1] Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer.
The epidermis, "epi" coming from the Greek language meaning "over" or "upon", is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface, which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.
Spinous cells are found in the superficial layers of the skin. They are found in the stratum spinosum (prickly layer, spinosum layer), which lies above the stratum basale (basal layer) and below the stratum granulosum (granular layer) of the epidermis. The spinous cells are arranged several layers thick to form a net-like covering. [1]
The dermis has two layers: the papillary dermis and the reticular layer. The papillary layer is the superficial layer that forms finger-like projections into the epidermis (dermal papillae), [5] and consists of highly vascularized, loose connective tissue. The reticular layer is the deep layer of the dermis and consists of the dense irregular ...
Histologic image showing a section of epidermis. Stratum basale labeled near bottom. The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the external covering of skin in mammals. The stratum basale is a single layer of columnar or cuboidal basal cells.
Sampling of human stratum corneum using a tape-stripping method [1] The stratum corneum (Latin for 'horned layer') is the outermost layer of the epidermis. Consisting of dead tissue, it protects underlying tissue from infection, dehydration, chemicals and mechanical stress. It is composed of 15–20 layers of flattened cells with no nuclei and ...
Histologic image of the epidermis with its layers named in white text.. The Malpighian layer (stratum mucosum or stratum malpighii) of the epidermis is generally defined as both the stratum basale (basal layer) and the thicker stratum spinosum (spinous layer/prickle cell layer) immediately above it as a single unit, [1] [2] although it is occasionally defined as the stratum basale specifically ...