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The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, [1] consisting of α4 and β2 subunits. [2] It is located in the brain , where activation yields post- and presynaptic excitation , [ 2 ] mainly by increased Na + and K + permeability.
320910 Ensembl ENSG00000105855 ENSMUSG00000025321 UniProt P26012 Q0VBD0 RefSeq (mRNA) NM_002214 NM_177290 RefSeq (protein) NP_002205 NP_796264 Location (UCSC) Chr 7: 20.33 – 20.42 Mb Chr 12: 119.12 – 119.2 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. Function This gene is a member of the integrin beta ...
3676 16401 Ensembl ENSG00000115232 ENSMUSG00000027009 UniProt P13612 Q00651 RefSeq (mRNA) NM_000885 NM_001316312 NM_010576 RefSeq (protein) NP_000876 NP_001303241 NP_034706 Location (UCSC) Chr 2: 181.46 – 181.54 Mb Chr 2: 79.09 – 79.16 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor ...
In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. [5] Upon binding with one of a number of alpha chains, CD18 is capable of forming multiple heterodimers, which play significant roles in cellular adhesion and cell surface signaling, as well as important roles in immune responses.
Eukaryotic Initiation Factor 2 (eIF2) is an eukaryotic initiation factor.It is required for most forms of eukaryotic translation initiation. eIF2 mediates the binding of tRNA i Met to the ribosome in a GTP-dependent manner. eIF2 is a heterotrimer consisting of an alpha (also called subunit 1, EIF2S1), a beta (subunit 2, EIF2S2), and a gamma (subunit 3, EIF2S3) subunit.
8516 241226 Ensembl ENSG00000077943 ENSMUSG00000026768 UniProt P53708 A2ARA8 RefSeq (mRNA) NM_001291494 NM_003638 NM_001001309 RefSeq (protein) NP_001278423 NP_003629 NP_001001309 NP_001395029 NP_001395030 NP_001395031 Location (UCSC) Chr 10: 15.51 – 15.72 Mb Chr 2: 12.11 – 12.31 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Integrin alpha-8 is a protein that in humans is ...
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The beta-2 adrenergic receptor (β 2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric G s proteins, increases cAMP, and, via downstream L-type calcium channel interaction, mediates physiologic responses such as smooth ...