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  2. Peptidoglycan - Wikipedia

    en.wikipedia.org/wiki/Peptidoglycan

    Peptidoglycan or murein is a unique large macromolecule, a polysaccharide, ... Peptidoglycan from Staphylococcus aureus was used as a vaccine to protect mice, ...

  3. Peptidoglycan recognition protein - Wikipedia

    en.wikipedia.org/wiki/Peptidoglycan_recognition...

    Human, [18] [58] mouse, [57] and porcine [74] PGLYRP2 are enzymes, N-acetylmuramoyl-L-alanine amidases, that hydrolyze the amide bond between the MurNAc and L-alanine, the first amino acid in the stem peptide in bacterial cell wall peptidoglycan. The minimal peptidoglycan fragment hydrolyzed by PGLYRP2 is MurNAc-tripeptide. [58]

  4. Tracheal cytotoxin - Wikipedia

    en.wikipedia.org/wiki/Tracheal_cytotoxin

    NOD-1 is a pattern recognition receptor that detects peptidoglycan. This receptor reacts weakly to TCT in humans, but robustly in mice. TCT is thought to work synergistically with LOS to mediate an inflammatory response, thus causing damage to ciliated epithelial cells. [14]

  5. Muramyl dipeptide - Wikipedia

    en.wikipedia.org/wiki/Muramyl_dipeptide

    Muramyl dipeptide is a component of bacterial peptidoglycan, a recognition structure or activator for nucleotide-binding oligomerization domain 2 (NOD2) protein. [1] It is a constituent of both Gram-positive and Gram-negative bacteria composed of N-acetylmuramic acid linked by its lactic acid moiety to the N-terminus of an L-alanine D-isoglutamine dipeptide. [1]

  6. Peptidoglycan recognition protein 2 - Wikipedia

    en.wikipedia.org/wiki/Peptidoglycan_recognition...

    In 2000, Dan Hultmark and coworkers discovered a family of 12 Peptidoglycan Recognition Protein (PGRP) genes in Drosophila melanogaster and by homology searches of available human and mouse sequences predicted the presence of long forms of human and mouse PGRPs, which they named PGRP-L by analogy to long forms of insect PGRPs.

  7. Can the 'coffee loophole' keep your hunger at bay?

    www.aol.com/coffee-loophole-keep-hunger-bay...

    An animal study found that giving mice lemon polyphenol supplements (antioxidant compounds in lemon) decreased body weight and body fat.

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