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Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease. [ 4 ] [ 1 ] Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. [ 4 ]
Hans Gerhard Creutzfeldt (June 2, 1885 – December 30, 1964) was a German neurologist and neuropathologist. [1] Although he is typically credited as the physician to first describe the Creutzfeldt–Jakob disease, this has been disputed. [1] [2] [3] He was born in Harburg an der Elbe and died in Munich.
Creutzfeldt–Jakob disease - degenerative CNS disorder, named after the authors who first described it. Topics referred to by the same term This disambiguation page lists articles associated with the title Creutzfeldt .
This was confirmed with the identification of a Kuru-like disease, called new variant Creutzfeldt–Jakob disease, in humans exposed to BSE. [50] Although the infectious disease model of TSE has been questioned in favour of a prion transplantation model that explains why cannibalism favours transmission, [ 51 ] the search for a viral agent was ...
Variant Creutzfeldt–Jakob disease (vCJD), formerly known as New variant Creutzfeldt–Jakob disease (nvCJD) and referred to colloquially as "mad cow disease" or "human mad cow disease" to distinguish it from its BSE counterpart, is a fatal type of brain disease within the transmissible spongiform encephalopathy family. [7]
He coined the term "Creutzfeldt–Jakob disease" to refer to a rapidly progressive neurodegenerative disease first described separately by the eponymous German neurologists. [ 4 ] Walther Spielmeyer and his laboratory team at Munich, 1927 (Spielmeyer at center front).
The United Kingdom was afflicted with an outbreak of bovine spongiform encephalopathy (BSE, also known as "mad cow disease"), and its human equivalent variant Creutzfeldt–Jakob disease (vCJD), in the 1980s and 1990s. Over four million head of cattle were slaughtered in an effort to contain the outbreak, and 178 people died after contracting ...
Jonathan Simms (1 June 1984 – 5 March 2011) was a man from Belfast, Northern Ireland, who contracted variant Creutzfeldt–Jakob disease (vCJD) in his late teenage years. He was given a post-diagnosis life expectancy of one year, similar to that of other young people who were diagnosed in the same age bracket.