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Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
[4] [8] [9] However, DHEA also has a variety of potential biological effects in its own right, binding to an array of nuclear and cell surface receptors, [10] and acting as a neurosteroid and modulator of neurotrophic factor receptors. [11] In the United States, DHEA is sold as an over-the-counter supplement, and medication called prasterone.
Prescription topical DHEA can be used by menopausal women to treat thinning vaginal tissue. Over-the-counter DHEA supplements are also available for men and women. DHEA is said to be good for:
Dehydroepiandrosterone sulfate, abbreviated as DHEA sulfate or DHEA-S, also known as androstenolone sulfate, is an endogenous androstane steroid that is produced by the adrenal cortex. [1] It is the 3β- sulfate ester and a metabolite of dehydroepiandrosterone (DHEA) and circulates in far greater relative concentrations than DHEA. [ 2 ]
Prasterone sulfate (brand names Astenile, Mylis, Teloin, others), also known as dehydroepiandrosterone sulfate (DHEA-S), is a naturally occurring androstane steroid which is marketed and used in Japan and other countries as a labor inducer in the treatment of insufficient cervical ripening and dilation during childbirth.
16α-Hydroxydehydroepiandrosterone sulfate (16α-OH-DHEA-S), also known as 16α-hydroxy-17-oxoandrost-5-en-3β-yl sulfate, is an endogenous, naturally occurring steroid and a metabolic intermediate in the production of estriol from dehydroepiandrosterone (DHEA) during pregnancy. [1] [2] It is the C3β sulfate ester of 16α-hydroxy-DHEA. [3] [4]
15α-Hydroxydehydroepiandrosterone sulfate, abbreviated as 15α-hydroxy-DHEA sulfate or 15α-OH-DHEA-S, also known as 15α-hydroxy-17-oxoandrost-5-en-3β-yl sulfate, is an endogenous, naturally occurring steroid and a metabolic intermediate in the production of estetrol from dehydroepiandrosterone (DHEA) during pregnancy.
Prasterone enanthate, also known as dehydroepiandrosterone enanthate (DHEA-E) and sold in combination with estradiol valerate under the brand name Gynodian Depot among others, is a weak androgen, estrogen, and neurosteroid medication which is used as a component of menopausal hormone therapy to treat menopausal symptoms in women.
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