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7-Ketodehydroepiandrosterone (7-keto-DHEA, 7-oxo-DHEA), also known as 7-oxoprasterone, is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). [ 1 ] [ 2 ] Pharmacodynamics
In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56] As DHEA-S can be converted back into DHEA, it serves as a circulating reservoir for DHEA, thereby extending the duration of DHEA. [57] [20] Metabolites of DHEA include DHEA-S, 7α-hydroxy-DHEA, 7β-hydroxy-DHEA, 7-keto-DHEA, 7α-hydroxyepiandrosterone, and 7β ...
The DHEA content in the daily recommended dose of Dexatrim Max ranges from 100–200 mg per day. [1] Side effects at this dose can include acne, hair loss, facial hair growth and deeper voice in women, stomach upset, and high blood pressure, particularly if the supplement is used for a longer period of time. [11]
Doses above 50 to 100 milligrams a day or taking DHEA for an extended period could up your odds of serious side effects. Samara Heisz/istockphoto DHEA Interactions and Risk Factors
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
At dosages of 50 mg or 100 mg per day, androstenedione had no effect on muscle strength or size, or on body fat levels. [15] One study used a daily dosage of 300 mg of androstenedione combined with several other supplements, and also found no increase in strength when compared to a control group that did not take the supplements.
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