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CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene. The mutations cause expression of a defective α chain or complete absence thereof, an essential part of high-affinity interleukin-2 (IL-2) receptors.
The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha (IL2RA), beta and the common gamma chain ().
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in February 2025 ) and then linked below. 2025
IL-2 binds to the IL-2 receptor, which has three forms, generated by different combinations of three different proteins, often referred to as "chains": α (alpha) (also called IL-2Rα, CD25, or Tac antigen), β (beta) (also called IL-2Rβ, or CD122), and γ (gamma) (also called IL-2Rγ, γ c, common gamma chain, or CD132); these subunits are also parts of receptors for other cytokines.
This is a list of people who died in the last 5 days with an article at the English Wikipedia. For people without an English Wikipedia page see: Wikipedia:Database reports/Recent deaths (red links). Generally updated at least daily, last time: 10:59, 14 February 2025 (UTC).
PDL2 or PDCD1LG2 (Programmed Cell Death 1 Ligand 2); on Dendritic cells, Macrophages etc. Ligand for PD-1 (CD279) CD274: PDL1 or PDCD1L1 (Programmed Cell Death 1 Ligand 1); expressed on T cells, NK cells, macrophages, myeloid DCs, B cells, epithelial cells, and vascular endothelial cells and others. Ligand for PD1 (CD279) and also CD80 (B7-1).
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List of medical professionals who died during the SARS outbreak; Fatality statistics in the Western Australian mining industry; List of countries by mortality rate; List of motor vehicle deaths in Iceland by year; Motorcycle fatality rate in U.S. by year; List of Mount Everest death statistics; List of multisport and triathlon fatalities