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  2. CD25 deficiency - Wikipedia

    en.wikipedia.org/wiki/CD25_deficiency

    CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene. The mutations cause expression of a defective α chain or complete absence thereof, an essential part of high-affinity interleukin-2 (IL-2) receptors.

  3. IL2RA - Wikipedia

    en.wikipedia.org/wiki/IL2RA

    The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha (IL2RA), beta and the common gamma chain ().

  4. List of human clusters of differentiation - Wikipedia

    en.wikipedia.org/wiki/List_of_human_clusters_of...

    In 2016, Novartis initiated an anti-GITR (GWN323) trial. [24] CD358: Death receptor 6 or tumor necrosis factor receptor superfamily member 21 (TNFRSF21), it activates the JNK and NF-κB pathways and is mostly expressed in the thymus, spleen and white blood cells. CD360: IL21R (Interleukin 21 receptor). It is a cytokine receptor for interleukin ...

  5. CD25 - Wikipedia

    en.wikipedia.org/?title=CD25&redirect=no

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  6. John List (murderer) - Wikipedia

    en.wikipedia.org/wiki/John_List_(murderer)

    John Emil List (September 17, 1925 – March 21, 2008) was an American mass murderer [1] and long-time fugitive.On November 9, 1971, he killed his wife, mother, and three children at their home in Westfield, New Jersey, and then disappeared.

  7. IL2RB - Wikipedia

    en.wikipedia.org/wiki/IL2RB

    16185 Ensembl ENSG00000100385 ENSMUSG00000068227 UniProt P14784 P16297 RefSeq (mRNA) NM_000878 NM_001346222 NM_001346223 NM_008368 RefSeq (protein) NP_000869 NP_001333151 NP_001333152 NP_032394 Location (UCSC) Chr 22: 37.13 – 37.18 Mb Chr 15: 78.36 – 78.38 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-2 receptor subunit beta is a protein that in humans is encoded by ...

  8. Basiliximab - Wikipedia

    en.wikipedia.org/wiki/Basiliximab

    Basiliximab is indicated for the prophylaxis of acute organ rejection in de-novo allogeneic renal transplantation. [3] It is to be used concomitantly with ciclosporin for microemulsion- and corticosteroid-based immunosuppression, in people with panel reactive antibodies less than 80%, or in a triple maintenance immunosuppressive regimen containing ciclosporin for microemulsion, corticosteroids ...

  9. Daclizumab - Wikipedia

    en.wikipedia.org/wiki/Daclizumab

    Daclizumab was used to treat adults with relapsing forms of multiple sclerosis. [6] It is administered subcutaneously. [7]In clinical trials, decreases of 45% in annualized relapse rate have been reported, as well as a 41% reduction in the proportion of patients who relapsed, and a 54% reduction in the number of new lesions. [7]