Search results
Results from the WOW.Com Content Network
This parallel artificial membrane permeability assay technique measures the permeability across specifically formulated lipid cocktail(s) found to be highly correlated with Caco-2 cultures, [105] [106] the gastrointestinal tract, [107] blood–brain barrier [108] and skin.
The concept of permeability is of importance in determining the flow characteristics of hydrocarbons in oil and gas reservoirs, [4] and of groundwater in aquifers. [5]For a rock to be considered as an exploitable hydrocarbon reservoir without stimulation, its permeability must be greater than approximately 100 md (depending on the nature of the hydrocarbon – gas reservoirs with lower ...
At low pore humidities (<75%), shrinkage is caused by a decrease of the disjoining pressure across nano-pores less than about 3 nm thick, filled by adsorbed water. The chemical processes of Portland cement hydration lead to another type of shrinkage, called the autogeneous shrinkage, which is observed in sealed specimens, i.e., at no moisture loss.
The more cholesterol a rat eats the lower the blood cholesterol. [16] During the first seven hours after ingestion of cholesterol, as absorbed fats are being distributed around the body within extracellular water by the various lipoproteins (which transport all fats in the water outside cells), the concentrations increase.
Hypocholesterolemia is the presence of abnormally low (hypo-) levels of cholesterol in the blood (-emia). A defect in the body's production of cholesterol can lead to adverse consequences as well. Cholesterol is an essential component of mammalian cell membranes and is required to establish proper membrane permeability and fluidity.
Cholesterol is the dynamic "glue" that holds the raft together. [3] Due to the rigid nature of the sterol group, cholesterol partitions preferentially into the lipid rafts where acyl chains of the lipids tend to be more rigid and in a less fluid state. [6] One important property of membrane lipids is their amphipathic character.
A pervious concrete street in 2005. Pervious concrete (also called porous concrete, permeable concrete, no fines concrete and porous pavement) is a special type of concrete with a high porosity used for concrete flatwork applications that allows water from precipitation and other sources to pass directly through, thereby reducing the runoff from a site and allowing groundwater recharge.
To date, PAMPA models have been developed that exhibit a high degree of correlation with permeation across a variety of barriers, including Caco-2 cultures, [2] [3] the gastrointestinal tract, [4] blood–brain barrier [5] and skin. The donor and/or acceptor compartments may contain solubilizing agents, or additives that bind the drugs as they ...