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Lacosamide, sold under the brand name Vimpat among others, is a medication used for the treatment of partial-onset seizures and primary generalized tonic-clonic seizures. [2] It is used by mouth or intravenously. [2] It is available as a generic medication. [4] [5]
lacosamide: Vimpat 28 October 2008 [65] lamotrigine: Lamictal 27 December 1994 [66] October 1991 [46] [51] May 1995 [51] levetiracetam: Keppra 30 November 1999 [67] 29 September 2000 [46] [68] 29 September 2000 [68] mephenytoin: Mesantoin 23 October 1946 [69] metharbital: Gemonil 1952 [70] [71]
Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]
The mechanism of action of phenytoin sodium. Sodium channels are: 1) Closed 2) Open 3) Inactive (phenytoin effect) Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels. [46] This blocks sustained high frequency repetitive firing of action potentials. This is accomplished by ...
Valnoctamide is a racemic compound with four stereoisomers, [10] all of which were shown to be more effective than valproic acid in animal models of epilepsy and one of which [(2S,3S]-valnoctamide) was considered to be a good candidate by Isoherranen, et al. for an anticonvulsant in August 2003.
Levetiracetam has not been found to be useful for treatment of neuropathic pain, [26] nor for treatment of essential tremors. [27] Levetiracetam has not been found to be useful for treating all developmental disorders within the autism spectrum; [28] [29] studies have only proven to be an effective treatment for partial, myoclonic, or tonic-clonic seizures associated with autism spectrum disorder.
Stiripentol, sold under the brand name Diacomit, is an anticonvulsant medication used for the treatment of Dravet syndrome - a serious genetic brain disorder. [5] [6]The most common side effects include loss of appetite, weight loss, insomnia (difficulty sleeping), drowsiness, ataxia (inability to co‑ordinate muscle movements), hypotonia (low muscle strength) and dystonia (muscle disorders).
Polysulfated glycosaminoglycan (PSGAG), sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the limpness, pain, and lowered range of motion caused by arthritis. [2]
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