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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Inflammatory involvement of tertiary syphilis begins at the adventitia of the aortic arch which progressively causes obliterative endarteritis of the vasa vasorum. [3] This leads to narrowing of the lumen of the vasa vasorum, causing ischemic injury of the medial aortic arch and then finally loss of elastic support and dilation of the vessel. [3]
Secondary syphilis. Syphilis is an STI caused by a bacterium. Untreated, it can lead to complications and death. [67] Clinical manifestations of syphilis include the ulceration of the uro-genital tract, mouth or rectum; if left untreated the symptoms worsen.
Treponema pallidum, formerly known as Spirochaeta pallida, is a microaerophilic, gram-negative, spirochaete bacterium with subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. [1] It is known to be transmitted only among humans and baboons. [2]
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...
An article titled "Epidemics of syphilis in the Russian Federation: trends, origins, and priorities for control", published in The Lancet, discussed syphilis trends in Russia. Like China, Russia basically eliminated the disease during the 1960s, though there was a slight increase during 1978 and 1979 with an estimated 28 cases per 100,000.
Cases of syphilis have hit record high numbers following a five-year trend, the Centers for Disease Control and Prevention said. A report published Jan. 30 examined the total cases of three ...
Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). [3]