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The high-current electron beam struck the patients with approximately 100 times the intended dose of radiation, and over a narrower area, delivering a potentially lethal dose of beta radiation. The feeling was described by patient Ray Cox as "an intense electric shock", causing him to scream and run out of the treatment room. [ 7 ]
Electron beam therapy is used in the treatment of superficial tumors like cancer of skin regions, or total skin (e.g. mycosis fungoides), diseases of the limbs (e.g. melanoma and lymphoma), nodal irradiation, and it may also be used to boost the radiation dose to the surgical bed after mastectomy or lumpectomy.
Electron-beam processing involves irradiation (treatment) of products using a high-energy electron-beam accelerator. Electron-beam accelerators utilize an on-off technology, with a common design being similar to that of a cathode ray television. Electron-beam processing is used in industry primarily for three product modifications:
External beam radiation therapy (EBRT) is a form of radiotherapy that utilizes a high-energy collimated beam of ionizing radiation, from a source outside the body, to target and kill cancer cells. The radiotherapy beam is composed of particles, which are focussed in a particular direction of travel using collimators [ 1 ] .
Conventional radiation techniques such as external beam radiotherapy (EBRT) following surgical removal of the tumor have several drawbacks: The tumor bed where the highest dose should be applied is frequently missed due to the complex localization of the wound cavity even when modern radiotherapy planning is used.
Radiation dermatitis (also known as radiodermatitis) is a skin disease associated with prolonged exposure to ionizing radiation. [3]: 131–2 Radiation dermatitis occurs to some degree in most patients receiving radiation therapy, with or without chemotherapy.
When a full bolus is applied, bolus thickness equal to the depth of the build-up region removes the skin-sparing effect of a megavoltage x-ray beam. On the other hand, there are boluses that do not require the selection of specific thicknesses to treat a certain depth.
Research in this area has focused on the three most common sources of radiation used for these applications, including gamma, electron beam, and x-ray radiation. [17] The mechanisms of radiation damage are different for polymers and metals, since dislocations and grain boundaries do not have real significance in a polymer.