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Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.Therefore, the first stage of myelinogenesis is often defined as the differentiation of oligodendrocyte progenitor cells (OPCs) or Schwann cell progenitors into their mature counterparts, [4] followed by myelin formation around axons.
Cortical white matter increases from childhood (~9 years) to adolescence (~14 years), most notably in the frontal and parietal cortices. [8] Cortical grey matter development peaks at ~12 years of age in the frontal and parietal cortices, and 14–16 years in the temporal lobes (with the superior temporal cortex being last to mature), peaking at about roughly the same age in both sexes ...
Myelination is only prevalent in a few brain regions at birth and continues into adulthood. The entire process is not complete until about 25–30 years of age. [24] Myelination is an important component of intelligence, and white matter quantity may be positively correlated with IQ test results in children. [24]
Children's brains contain more "silent synapses" that are inactive until recruited as part of neuroplasticity and flexible learning or memories. [38] [39] Neuroplasticity is heightened during critical or sensitive periods of brain development, mainly referring to brain development during child development. [40]
The cortex is the outer layer of the brain and is composed of up to six layers. Neurons formed in the ventricular zone migrate to their final locations in one of the six layers of the cortex. [ 1 ] The process occurs from embryonic day 10 to 17 in mice and between gestational weeks seven to 18 in humans.
The infant brain will increase in size by a factor of up to 5 by adulthood, reaching a final size of approximately 86 (± 8) billion neurons. [4] Two factors contribute to this growth: the growth of synaptic connections between neurons and the myelination of nerve fibers; the total number of neurons, however, remains the same.
A 7-month-old baby born in New Jersey is being considered the first to ever survive his rare condition past birth.
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.