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There are several causes of toxic optic neuropathy. [1] Among these are: ingestion of methanol (wood alcohol), ethylene glycol (automotive antifreeze), disulfiram (used to treat chronic alcoholism), halogenated hydroquinolones (amebicidal medications), ethambutol and isoniazid (tuberculosis treatment), and antibiotics such as linezolid and chloramphenicol as well as chloroquine and the related ...
The general cause of this disease appears to be prolonged and heavy consumption of alcohol accompanied by a nutritional deficiency. However, there is ongoing debate over the active mechanisms, [6] [7] including whether the main cause is the direct toxic effect of alcohol itself or whether the disease is a result of alcoholism-related ...
After excessive drinking, stupor and unconsciousness can both occur. Extreme levels of consumption can cause alcohol poisoning and death; a concentration in the blood stream of 0.36% will kill half of those affected. [2] [3] [4] Alcohol may also cause death indirectly by asphyxiation, caused from vomiting. Alcohol can greatly exacerbate sleep ...
This usually happens when a blood alcohol level is about twice the legal limit, [about] 0.16% or so." Not remembering what you did while drinking may be stressful in the short term. However, it ...
May Cause Alcohol Dependence “Regular or excessive alcohol consumption can lead to alcohol-related problems, including addiction, liver damage, and increased risk of certain cancers,” says ...
In jurisdictions in the U.S., maximum blood alcohol levels for legal driving are about 17 to 22 mM. [ 67 ] [ 68 ] In the upper range of recreational ethanol concentrations of 20 to 50 mM, depression of the central nervous system is more marked, with effects including complete drunkenness, profound sedation, amnesia, emesis, hypnosis, and ...
Excessive levels of alcohol consumption increase risk for six cancers, from head and neck, to stomach cancers, the report said. In the U.S., more than 5% of cancers were linked to alcohol ...
Alcohol metabolism. ALDH1 is an isozyme of aldehyde dehydrogenase.A structural mutation in the gene of ALDH1, commonly found in East Asians, results in low levels of functional ALDH1 enzyme and thus, higher blood acetaldehyde levels.