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Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]
Viagra could lead to more serious side effects, such as: Priapism (a painful, long-lasting arousal) Vision loss. Chest pain. Flu-like symptoms. Heart attack. Stroke. Dizziness. Sudden low blood ...
In fact, studies show that just one dose of Viagra has a 70 to 80 percent success rate for treating ED. PDE5 stands for phosphodiesterase type 5, an enzyme that plays an important role in ...
Viagra usually starts working 30 to 60 minutes after taking it. But simply swallowing the little blue pill won’t automatically make you hard — you still have to be aroused, either through ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
The duration of action of a drug is the length of time that particular drug is effective. [5] Duration of action is a function of several parameters including plasma half-life, the time to equilibrate between plasma and target compartments, and the off rate of the drug from its biological target. [6]
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
In clinical trials of Viagra, more than 82 percent of men with ED reported an improvement in their climaxes after using Viagra at a dosage of 100mg (the highest dosage prescribed for ED).