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  2. Brain-derived neurotrophic factor - Wikipedia

    en.wikipedia.org/wiki/Brain-derived_neurotrophic...

    Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [ 7 ] [ 8 ] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4 /NT-5.

  3. Development of the nervous system - Wikipedia

    en.wikipedia.org/wiki/Development_of_the_nervous...

    It is now clear that factors produced by a number of sources contribute to neuronal survival. Nerve Growth Factor (NGF): Rita Levi Montalcini and Stanley Cohen purified the first trophic factor, Nerve Growth Factor (NGF), for which they received the Nobel Prize. There are three NGF-related trophic factors: BDNF, NT3, and NT4, which regulate ...

  4. Molecular neuroscience - Wikipedia

    en.wikipedia.org/wiki/Molecular_neuroscience

    Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics and epigenetics on neuronal development, and the molecular basis for neuroplasticity and ...

  5. FOSB - Wikipedia

    en.wikipedia.org/wiki/FOSB

    2354 14282 Ensembl ENSG00000125740 ENSMUSG00000003545 UniProt P53539 P13346 RefSeq (mRNA) NM_001114171 NM_006732 NM_008036 NM_001347586 RefSeq (protein) NP_001107643 NP_006723 NP_001334515 NP_032062 Location (UCSC) Chr 19: 45.47 – 45.48 Mb Chr 7: 19.04 – 19.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein fosB, also known as FosB and G0/G1 switch regulatory protein 3 ...

  6. Activity-regulated cytoskeleton-associated protein - Wikipedia

    en.wikipedia.org/wiki/Activity-regulated...

    Arc protein is widely considered to be important in neurobiology because of its activity regulation, localization, and utility as a marker for plastic changes in the brain. Dysfunction in the production of Arc protein has been implicated as an important factor in understanding various neurological conditions, including amnesia , [ 9 ] Alzheimer ...

  7. Agouti-related peptide - Wikipedia

    en.wikipedia.org/wiki/Agouti-related_peptide

    11604 Ensembl ENSG00000159723 ENSMUSG00000005705 UniProt O00253 P56473 RefSeq (mRNA) NM_001138 NM_001271806 NM_007427 RefSeq (protein) NP_001129 NP_001258735 NP_031453 Location (UCSC) Chr 16: 67.48 – 67.48 Mb Chr 8: 106.29 – 106.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the ...

  8. Dynorphin - Wikipedia

    en.wikipedia.org/wiki/Dynorphin

    One proposed molecular mechanism for increased dynorphin levels involves transcriptional regulation by CREB (3’, 5’-monophosphate response element binding protein). According to the model proposed by Carlezon et al., use of cocaine increases the expression of cAMP and cAMP-dependent protein kinase . [18]

  9. Neuropeptide Y - Wikipedia

    en.wikipedia.org/wiki/Neuropeptide_Y

    It has been found that in breast muscle, ATP production genes (uncoupling protein, UCP; nuclear factor erythroid 2 like 2, NFE2L2) and a dynamics gene (mitofusin 1, MFN1) were upregulated (P < 0.05) at a low dose of NPY, while a high dose decreased (P < 0.05) markers of mitochondrial dynamics (mitofusin 2, MFN2; OPA1 mitochondrial dynamin-like ...