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  2. JWH-073 - Wikipedia

    en.wikipedia.org/wiki/JWH-073

    JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a full agonist [3] at both the CB 1 and CB 2 cannabinoid receptors. It is somewhat selective for the CB 1 subtype, with affinity at this subtype approximately 5× the affinity at CB 2 . [ 4 ]

  3. JWH-018 - Wikipedia

    en.wikipedia.org/wiki/JWH-018

    JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]

  4. Synthetic cannabinoids - Wikipedia

    en.wikipedia.org/wiki/Synthetic_cannabinoids

    There are several synthetic cannabinoid families (e.g., AM-xxx, CP-xx,xxx, HU-xx, JWH-xxx) which are classified by the creator of the substance (e.g., JWH stands for John W. Huffman), which can include several substances with different base structures such as classical cannabinoids and unrelated naphthoylindoles. [11]

  5. List of JWH cannabinoids - Wikipedia

    en.wikipedia.org/wiki/List_of_JWH_cannabinoids

    JWH-425 [17] Naphthoylindole: 54 ± 11: 10 ± 0.4: CB 2 (5.4x) See also. List of AM cannabinoids; List of CP cannabinoids; List of HU cannabinoids; List of ...

  6. John W. Huffman - Wikipedia

    en.wikipedia.org/wiki/John_W._Huffman

    As JWH-018 is more potent and easy to make, Huffman believes it is a more widely used synthetic cannabinoid of the JWH series. [8] Legal advisor

  7. JWH-307 - Wikipedia

    en.wikipedia.org/wiki/JWH-307

    JWH-307 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB 1 and CB 2 receptors. It is somewhat selective for the CB 2 subtype, with a K i of 7.7 nM at CB 1 vs 3.3 nM at CB 2 . [ 1 ]

  8. JWH-200 - Wikipedia

    en.wikipedia.org/wiki/JWH-200

    JWH-200 (WIN 55,225 [1]) is an analgesic chemical from the aminoalkylindole family that acts as a cannabinoid receptor agonist. Its binding affinity, K i at the CB 1 receptor is 42 nM, around the same as that of THC, [2] but its analgesic potency in vivo was higher than that of other analogues with stronger CB 1 binding affinity in vitro, [3] around 3 times that of THC but with less sedative ...

  9. JWH-098 - Wikipedia

    en.wikipedia.org/wiki/JWH-098

    JWH-098 is a synthetic cannabinoid receptor agonist from the naphthoylindole family. It is the indole 2-methyl derivative of a closely related compound JWH-081 , but has markedly different affinity for the CB 1 and CB 2 receptors.