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Vitamin C supplements among other dietary supplements at a US drug store. Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results.
C 6 H 6 O 6 • − + L• + H 2 O + H + → C 6 H 8 O 7 + LH 2 C 6 H 6 O 6 • − + H 2 O + H + → C 6 H 8 O 7 + C 6 H 7 O − 6. Aqueous solutions of dehydroascorbate are unstable, undergoing hydrolysis with a half-life of 5–15 minutes at 37 °C (99 °F). Decomposition products include diketogulonic acid, xylonic acid, threonic acid and ...
The probable mechanism of vitamin C reduction, intragastric pH elevated into alkalinity, would apply to all other PPI drugs, though not necessarily to doses of PPIs low enough to keep the stomach slightly acidic. [25] In another study, 40 mg/day of omeprazole lowered the fasting gastric vitamin C levels from 3.8 to 0.7 μg/mL. [26]
[106] [107] A study using 250 mg and 1000 mg doses of vitamin C along with other antioxidants to treat people with AIDS did not find any benefit. [ 108 ] A meta analysis in 2010 (updated in 2017 with different results) found that micronutrient supplementation decreased the risk of death and improved outcomes in pregnant women with HIV in Africa.
An equilibrium constant is related to the standard Gibbs free energy change for the reaction = R is the gas constant and T is the absolute temperature. At 25 °C, ΔG ⊖ = (−5.708 kJ mol −1) ⋅ log β. Free energy is made up of an enthalpy term and an entropy term.
On October 17, 2012, researchers reported on a double-blind study of 14,641 male U.S. physicians initially aged 50 years or older (mean age of 64.3, standard deviation 9.2 years), that began in 1997 with treatment and follow-up through June 1, 2011.
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