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Desvenlafaxine is a synthetic form of the isolated major active metabolite of venlafaxine, and is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). When most normal metabolizers take venlafaxine, approximately 70% of the dose is metabolized into desvenlafaxine, so the effects of the two drugs are expected to be very similar. [18]
Most SNRIs including venlafaxine, desvenlafaxine, and duloxetine, are several fold more selective for serotonin over norepinephrine, while milnacipran is three times more selective for norepinephrine than serotonin.
Desvenlafaxine, sold under the names Pristiq and Khedezla, is an SNRI used primarily to treat major depressive disorder in adults. It can also be prescribed off-label to treat hot flashes for ...
Serotonin–norepinephrine reuptake inhibitors include: Desvenlafaxine (Pristiq) Duloxetine (Cymbalta) Levomilnacipran (Fetzima) Milnacipran (Ixel, Savella, Milnaneurax) Venlafaxine (Effexor, Trevilor)
List of SNRIs. Numerous SNRI antidepressants are currently prescribed to treat depression, as well as other mood disorders.They include: Desvenlafaxine (Pristiq) has been used as a treatment for ...
SNRIs are another class of modern antidepressants. Common SNRIs include Cymbalta (duloxetine), Effexor XR (venlafaxine) and Pristiq (desvenlafaxine). Tricyclic antidepressants (TCAs).
Pristiq (desvenlafaxine) – an antidepressant of the SNRI class; Prolixin (fluphenazine) – typical antipsychotic; Provigil - used to treat excessive sleepiness and narcolepsy; Prozac – an antidepressant of the SSRI class; Luminal (phenobarbital) – a barbiturate with sedative and hypnotic properties
SNRIs, such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima) and venlafaxine (Effexor XR). Tricyclic antidepressants, such as desipramine (Norpramin), doxepin ...
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