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[59] [64] In 1908, a Japanese research group led by Ryukichi Inada and Yutaka Ito first identified this bacterium as the causative agent of leptospirosis [65] and noted its presence in rats in 1916. [66] Japanese coal mine workers frequently contracted leptospirosis. In Japan, the organism was named Spirocheta icterohaemorrhagiae. The Japanese ...
Medications are usually not needed as hand, foot, and mouth disease is a viral disease that typically resolves on its own. Under research [15] [16] Sin Nombre virus: Hantavirus Pulmonary Syndrome (HPS) No Heartland virus: Heartland virus disease No Helicobacter pylori: Helicobacter pylori infection No Escherichia coliO157:H7, O111 and O104:H4
An etiological agent of disease may require an independent co-factor, and be subject to a promoter (increases expression) to cause disease. An example of all the above, which was recognized late, is that peptic ulcer disease may be induced by stress, requires the presence of acid secretion in the stomach, and has primary etiology in ...
It has long been suspected as a causative agent in Crohn's disease in humans, [4] [5] but studies have been unable to show definite correlation. [6] One study has argued that the presence of antibodies against Mycobacterium avium subspecies paratuberculosis is associated with increased propensity of patients with Crohn's disease to receive ...
In 1916, he described a disease with the symptoms urethritis, conjunctivitis and arthritis, which became known as Reiter's syndrome. Reiter was born in Reudnitz, near Leipzig in the German Empire . He studied medicine at Leipzig and Breslau (now Wrocław ), and received a doctorate from Tübingen on the subject of tuberculosis .
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Nonetheless, Koch was already aware that the causative agent of cholera, Vibrio cholerae, could be found in both sick and healthy people, invalidating his first postulate. [ 6 ] [ 9 ] Since the 1950s, Koch's postulates have been treated as obsolete for epidemiology research, but they are still taught to emphasize historical approaches to ...