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Inflammation is one common cause that results in the sensitization of nociceptors. Normally hyperalgesia ceases when inflammation goes down, however, sometimes genetic defects and/or repeated injury can result in allodynia: a completely non-noxious stimulus like light touch causes extreme pain. Allodynia can also be caused when a nociceptor is ...
Inflammation is a generic response, and therefore is considered a mechanism of innate immunity, whereas adaptive immunity is specific to each pathogen. [2] Inflammation is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out ...
Back pain. When your back aches and there’s no obvious cause (like lifting heavy boxes or falling), inflammation could be the root cause.Inflammatory back pain tends to come on gradually and ...
swelling of affected tissues, such as the upper throat during the common cold or joints affected by rheumatoid arthritis; increased production of mucus, which can cause symptoms like a runny nose or a productive cough; pain, either local pain, such as painful joints or a sore throat, or affecting the whole body, such as body aches; and
DAMPs in plants have been found to stimulate a fast immune response, but without the inflammation that characterizes DAMPs in mammals. [34] Just as with mammalian DAMPs, plant DAMPs are cytosolic in nature and are released into the extracellular space following damage to the cell caused by either trauma or pathogen. [35]
An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors. These include a wide variety of different toxins, viruses, intra- and extracellular bacteria, protozoa, helminths, and fungi which could cause serious problems to the health of the host organism if not cleared from the body.
In anatomy, the interstitium is a contiguous fluid-filled space existing between a structural barrier, such as a cell membrane or the skin, and internal structures, such as organs, including muscles and the circulatory system. [1] [2] The fluid in this space is called interstitial fluid, comprises water and solutes, and drains into the lymph ...
Gum disease is an infection and inflammation of the tissues surrounding and supporting teeth. There are two primary forms: gingivitis and periodontitis. Gingivitis is the mildest form and is quite ...