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  2. Biochemical switches in the cell cycle - Wikipedia

    en.wikipedia.org/wiki/Biochemical_switches_in...

    Positive feedback loops play a role by switching cells from low to high Cdk-activity. The interaction between the two types of loops is evident in mitosis. While positive feedback initiates mitosis, a negative feedback loop promotes the inactivation of the cyclin-dependent kinases by the anaphase-promoting complex.

  3. Positive feedback - Wikipedia

    en.wikipedia.org/wiki/Positive_feedback

    Positive feedback occurs when a gene activates itself directly or indirectly via a double negative feedback loop. Genetic engineers have constructed and tested simple positive feedback networks in bacteria to demonstrate the concept of bistability. [28] A classic example of positive feedback is the lac operon in E. coli. Positive feedback plays ...

  4. Cell signaling - Wikipedia

    en.wikipedia.org/wiki/Cell_signaling

    Neurotransmitters represent another example of a paracrine signal. Some signaling molecules can function as both a hormone and a neurotransmitter. For example, epinephrine and norepinephrine can function as hormones when released from the adrenal gland and are transported to the heart by way of the blood stream.

  5. System archetype - Wikipedia

    en.wikipedia.org/wiki/System_archetype

    Reinforcing feedback (or amplifying feedback) accelerates the given trend of a process. If the trend is ascending, the reinforcing (positive) feedback will accelerate the growth. If the trend is descending, it will accelerate the decline. Falling of an avalanche is an example of the reinforcing feedback process. [1]

  6. Unconditional positive regard - Wikipedia

    en.wikipedia.org/wiki/Unconditional_positive_regard

    Unconditional positive regard, a concept initially developed by Stanley Standal in 1954, [1] later expanded and popularized by the humanistic psychologist Carl Rogers in 1956, is the basic acceptance and support of a person regardless of what the person says or does, especially in the context of client-centred therapy. [2]

  7. Biological applications of bifurcation theory - Wikipedia

    en.wikipedia.org/wiki/Biological_applications_of...

    Example of a biological network between genes and proteins that controls entry into S phase. However, with knowledge of network interactions and a set of parameters for the proteins and protein interactions (usually obtained through empirical research), it is often possible to construct a model of the network as a dynamical system .

  8. Paracrine signaling - Wikipedia

    en.wikipedia.org/wiki/Paracrine_signaling

    Paracrine signaling between neighboring cells creates this positive feedback loop. Thus, the constitutive transcription of upregulated proteins form ideal environments for tumors to arise. [ 12 ] Effectively, multiple bindings of ligands to the RTK receptors overstimulates the Ras-Raf-MAPK pathway, which overexpresses the mitogenic and invasive ...

  9. Hodgkin cycle - Wikipedia

    en.wikipedia.org/wiki/Hodgkin_Cycle

    The Hodgkin cycle represents a positive feedback loop in which an initial membrane depolarization leads to uncontrolled deflection of the membrane potential to near V Na. The initial depolarization must reach or surpass a certain threshold in order to activate voltage-gated Na + channels .