Search results
Results from the WOW.Com Content Network
John Frederick Joseph Cade AO [1] [2] [3] (18 January 1912 – 16 November 1980) was an Australian psychiatrist who in 1948 discovered the effects of lithium carbonate as a mood stabilizer in the treatment of bipolar disorder, then known as manic depression. At a time when the standard treatments for psychosis were electroconvulsive therapy and ...
A bottle of lithium capsules. Lithium is the prototypical mood stabilizer. A mood stabilizer is a psychiatric medication used to treat mood disorders characterized by intense and sustained mood shifts, such as bipolar disorder and the bipolar type of schizoaffective disorder.
Certain lithium compounds, also known as lithium salts, are used as psychiatric medication, [5] primarily for bipolar disorder and for major depressive disorder. [5] Lithium is taken orally (by mouth). [5] Common side effects include increased urination, shakiness of the hands, and increased thirst. [5]
In 1949, the Australian John Cade discovered that lithium salts could control mania, reducing the frequency and severity of manic episodes. This introduced the now popular drug lithium carbonate to the mainstream public, as well as being the first mood stabilizer to be approved by the U.S. Food & Drug Administration .
Lithium prevents mood relapse and works especially well in BP-II patients who experience rapid-cycling. [53] Almost all BP-II patients who take lithium have a decrease in the amount of time they spend ill and a decrease in mood episodes. [53] Along with medication, other forms of therapy have been shown to be beneficial for BP-II patients.
The history of the medications used in mental disorders has developed a lot through years. The discovery of modern drugs prevailed during the 20th century. Lithium, a mood stabilizer, was discovered as a treatment of mania, by John F. Cade in 1949, "and Hammond (1871) used lithium bromide for 'acute mania with depression'". [14]
Lithium citrate was removed from 7Up in 1948 [5] after the Food and Drug Administration banned its use in soda. [6] Lithium citrate is used as a mood stabilizer and is used to treat mania, hypomania, depression and bipolar disorder. [7] It can be administered orally in the form of a syrup. [7]
Antimanic drugs are psychotropic drugs that are used to treat symptoms of mania.Though there are different causes of mania, the majority is caused by bipolar disorder, therefore antimanic drugs are mostly similar to drugs treating bipolar disorder.