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Certain lithium compounds, also known as lithium salts, are used as psychiatric medication, [5] primarily for bipolar disorder and for major depressive disorder. [5] Lithium is taken orally (by mouth). [5] Common side effects include increased urination, shakiness of the hands, and increased thirst. [5]
John Frederick Joseph Cade AO [1] [2] [3] (18 January 1912 – 16 November 1980) was an Australian psychiatrist who in 1948 discovered the effects of lithium carbonate as a mood stabilizer in the treatment of bipolar disorder, then known as manic depression. At a time when the standard treatments for psychosis were electroconvulsive therapy and ...
A bottle of lithium capsules. Lithium is the prototypical mood stabilizer. A mood stabilizer is a psychiatric medication used to treat mood disorders characterized by intense and sustained mood shifts, such as bipolar disorder and the bipolar type of schizoaffective disorder.
Onset of Bipolar Disorder. Signs of bipolar disorder generally emerge in young adulthood. Research suggests that 70 percent of people with bipolar disorder experience their first manic episode ...
Antipsychotics are drugs used to treat various symptoms of psychosis, such as those caused by psychotic disorders or schizophrenia. Atypical antipsychotics are also used as mood stabilizers in the treatment of bipolar disorder , and they can augment the action of antidepressants in major depressive disorder . [ 22 ]
A 2008 Cochrane systematic review found limited evidence to support the use of Omega-3 fatty acids to improve depression but not mania as an adjunct treatment for bipolar disorder. Omega-3 fatty acids may be found in fish, fish oils , algae , and to a lesser degree in other foods such as flaxseed , flaxseed oil and walnuts .
Lithium has the best overall evidence and is considered an effective treatment for acute manic episodes, preventing relapses, and bipolar depression. [144] [145] Lithium reduces the risk of suicide, self-harm, and death in people with bipolar disorder. [146] Lithium is preferred for long-term mood stabilization. [68]
“The event or death may have been related to the underlying disease being treated, may have been caused by some other product being used at the same time, or may have occurred for other reasons.” The Times story also cited a buprenorphine study by researchers in Sweden that looked at “100 autopsies where buprenorphine had been detected.”