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The Human alphaherpesvirus 1 virus can be classified into six clades. [2] Four of these occur in East Africa, one in East Asia and one in Europe and North America. This suggests that the virus may have originated in East Africa. The most recent common ancestor of the Eurasian strains appears to have evolved ~60,000 years ago. [3]
Herpes simplex virus 1 (cold sores) and 2 (genital herpes) (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and ...
Pseudorabies virus is the causative agent of Aujeszky's disease in pigs and Bovine herpesvirus 1 is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. [1] [2] Mammals serve as natural hosts. There are currently 45 species in this subfamily, divided among 5 genera with one species unassigned to a genus.
Nine herpesvirus types are known to primarily infect humans, [7] at least five of which are extremely widespread among most human populations, and which cause common diseases: herpes simplex 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial and genital herpes), varicella zoster (VZV or HHV-3; the cause ...
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[1] [3] Beremagene geperpavec is the first approved gene therapy to use herpes-simplex virus type 1 as a vector. [ 4 ] [ 3 ] Beremagene geperpavec is a genetically modified (engineered in a laboratory) herpes-simplex virus used to deliver normal copies of the COL7A1 gene to the wounds.
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As of 2020, there have been 50 documented cases of human B virus infection since the identification of the virus in 1932, 21 of which led to death. [29] At least 20 of the patients developed some degree of encephalitis. [30] [31] B virus is the only identified old-world-monkey herpesvirus that displays severe pathogenicity in humans. [citation ...
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