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As previously described, gradual genetic drift across populations (isolation by distance) and limited gene dispersal can account for some of the genetic and phenotypic divergence across populations, but there are alternative models besides isolation by distance that can contribute to these differences as well.
Genetic divergence will always accompany reproductive isolation, either due to novel adaptations via selection and/or due to genetic drift, and is the principal mechanism underlying speciation. On a molecular genetics level, genetic divergence is due to changes in a small number of genes in a species, resulting in speciation. [2]
A genetic isolate is a population of organisms that has little to no genetic mixing with other organisms of the same species due to geographic isolation or other factors that prevent reproduction. Genetic isolates form new species through an evolutionary process known as speciation .
The genetics of ethological isolation barriers will be discussed first. Pre-copulatory isolation occurs when the genes necessary for the sexual reproduction of one species differ from the equivalent genes of another species, such that if a male of species A and a female of species B are placed together they are unable to copulate.
Figure 1: Genetic distance map by Cavalli-Sforza et al. (1994) [1] Genetic distance is a measure of the genetic divergence between species or between populations within a species, whether the distance measures time from common ancestor or degree of differentiation. [2] Populations with many similar alleles have small genetic distances. This ...
Allochronic speciation (also known as allochronic isolation, or temporal isolation) is a form of speciation (specifically ecological speciation) arising from reproductive isolation that occurs due to a change in breeding time that reduces or eliminates gene flow between two populations of a species.
IBD mapping can be seen as a new form of association analysis that increases the power to map genes or genomic regions containing multiple rare disease susceptibility variants. [ 7 ] [ 15 ] Using simulated data, Browning and Thompson showed that IBD mapping has higher power than association testing when multiple rare variants within a gene ...
In population genetics, gene flow (also known as migration and allele flow) is the transfer of genetic material from one population to another. If the rate of gene flow is high enough, then two populations will have equivalent allele frequencies and therefore can be considered a single effective population.