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Adhesion is the tendency of dissimilar particles or surfaces to cling to one another. (Cohesion refers to the tendency of similar or identical particles and surfaces ...
Arginylglycylaspartic acid (RGD) is the most common peptide motif responsible for cell adhesion to the extracellular matrix (ECM), found in species ranging from Drosophila to humans.
The process is highly regulated by cell adhesion molecules, particularly, the addressin also known as MADCAM1. This antigen is known for its role in tissue-specific adhesion of lymphocytes to high endothelium venules. [23] Through these interactions they play a crucial role in orchestrating circulating lymphocytes.
An increased residence time through adhesion to the mucosal surface, such as in the eye or the nose can lead to an improved absorption of the drug. [ citation needed ] Long-duration continuous imaging of diverse organs (via a wearable bioadhesive stretchable high-resolution ultrasound imaging patch, potentially enabling novel diagnostic and ...
Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
The strength of adhesion depends on many factors, including the means by which it occurs. In some cases, an actual chemical bond occurs between adhesive and substrate. Thiolated polymers , for example, form chemical bonds with endogenous proteins such as mucus glycoproteins, integrins or keratins via disulfide bridges. [ 40 ]
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Mucoadhesion involves several types of bonding mechanisms, and it is the interaction between each process that allows for the adhesive process. The major categories are wetting theory, adsorption theory, diffusion theory, electrostatic theory, and fracture theory. [5]