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Heat is required to decarboxylate the non-psychoactive phytocannabinoid THCA to its psychoactive form, THC. Likewise, CBDA turns into CBD. From hemp plant material in an oven, cannabinoid concentration plots (time/temp) show THC: [16] STP 0 minutes 0.20mg/g; 140-160C 20 minutes 0.27mg/g; 140-160C 60 minutes 0.05-0.15mg/g
The decarboxylation of this compound by heat is essential for the psychoactive effect of smoked cannabis, and depends on conversion of the enol to a keto group when the alpha carbon is protonated. Upon heating, Δ9-tetrahydrocannabinolic acid decarboxylates to give the psychoactive compound Δ9- Tetrahydrocannabinol . [ 13 ]
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
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Tincture of cannabis, sometimes known as green dragon, is an alcoholic cannabis concentrate.The solubility of THC in ethanol is greater than 1 g/mL. [1]According to the European Medicines Agency (EMA) cannabis tinctures (tincturea) are a type of liquid cannabis extract obtained using ethanol, water, glycerol, propylene glycol and fatty oils as extraction solvents, depending on the type of ...
A man smoking cannabis in Kolkata, India. Cannabis consumption refers to the variety of ways cannabis is consumed, among which inhalation (smoking and vaporizing) and ingestion are most common. All consumption methods involve heating the plant's THCA to decarboxylate it into THC, either at the time of consumption or during preparation. Salves ...
Delta-9-THCO and delta-8-THCO do not occur naturally in the cannabis plant and can only be obtained synthetically, and therefore do not fall under the definition of hemp…Thus, Δ9-THC-O and Δ8-THC-O meet the definition of 'tetrahydrocannabinols,' and they [and products containing Δ9-THC-O and Δ8-THC-O] are controlled in schedule I by 21 U ...
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