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Leukodystrophy is characterized by specific symptoms, including decreased motor function, muscle rigidity, and eventual degeneration of sight and hearing. While the disease is fatal, the age of onset is a key factor, as infants have a typical life expectancy of 2–8 years, while adults typically live more than a decade after onset.
Symptoms include cerebellar ataxia, spasticity, optic atrophy, epilepsy, [1] loss of motor functions, irritability, vomiting, coma, [2] and even fever has been tied to VWM. [3] The neurological disorders and symptoms which occur with VWM are not specific to countries; they are the same all over the world. [ 4 ]
These symptoms first start out with dysfunctions of the autonomic nervous system which result in symptoms such as abnormal functioning of both the bladder and bowel, recurrent blood pressure drops whenever patients stand up, and male erectile dysfunction. [8] [9] [10] Rarely, anhidrosis might also occur alongside these symptoms. [9] [8] [11] [10]
Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal viral disease characterized by progressive damage (-pathy) or inflammation of the white matter (leuko-) of the brain (-encephalo-) at multiple locations (multifocal). It is caused by the JC virus, which is normally present and kept under control by the immune system. The ...
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The disease presents with various signs and symptoms affecting different parts of the body. In the head, patients exhibit macrocephaly. This is characterized by megalencephaly, which is the enlargement of the brain leading to an increase in the size of the actual head. [3] In the central nervous system, several symptoms are observed.
Most tick-borne diseases are serious, but there's a particularly bad one to look out for if you live in Minnesota, Wisconsin or the Northeast.
Australia reported its first human case of A(H5N1) infection in May, noting there were no signs of transmission. It has however found more poultry cases of H7 bird flu on farms in Victoria state.