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Cerebral perfusion pressure, or CPP, is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion). It must be maintained within narrow limits because too little pressure could cause brain tissue to become ischemic (having inadequate blood flow), and too much could raise intracranial pressure (ICP).
Cancer is a group of diseases that involve abnormal increases in the number of cells, with the potential to invade or spread to other parts of the body. [1] Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other parts of the body. [ 1 ]
Elderly rodents typically die of cancer or kidney disease, but not of cardiovascular disease. In humans, the relative incidence of cancer increases exponentially with age for most cancers, but levels off or may even decline by age 60–75 [3] (although colon/rectal cancer continues to increase). [4]
For example, various Global Burden of Disease Studies investigate such factors and quantify recent developments – one such systematic analysis analyzed the (non)progress on cancer and its causes during the 2010–19-decade, indicating that 2019, ~44% of all cancer deaths – or ~4.5 M deaths or ~105 million lost disability-adjusted life years ...
CPP: cerebral perfusion pressure: CPPD: calcium pyrophosphate cyclic perimenstrual pain and discomfort [1] (premenstrual syndrome) CPR: cardiopulmonary resuscitation: CPT: Current Procedural Terminology: CR: complete remission (complete response) controlled release: Cr: creatinine: CRC: colorectal cancer: CrCl: creatinine clearance
Waldenström's macroglobulinemia (also known as lymphoplasmacytic lymphoma) is a lymphoproliferative disease that involves an abnormal increase of lymphocytes within the bone marrow, creasing disruption of normal red blood cell production. [76] Nodal marginal zone B cell lymphoma: Splenic marginal zone lymphoma
Because cancer is a class of diseases, [7] [255] it is unlikely that there will ever be a single "cure for cancer" any more than there will be a single treatment for all infectious diseases. [256] Angiogenesis inhibitors were once incorrectly thought to have potential as a " silver bullet " treatment applicable to many types of cancer. [ 257 ]
Traumatic brain injury can cause dangerously raised intracranial pressure. Pressure reactivity index or PRx is a tool for monitoring cerebral autoregulation in the intensive care setting for patients with severe traumatic brain injury or subarachnoid haemorrhage, in order to guide therapy to protect the brain from dangerously high or low cerebral blood flow.