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2. Humanized antibody - Wikipedia

   en.wikipedia.org/wiki/Humanized_antibody

   Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans. [ 1 ] [ 2 ] The process of "humanization" is usually applied to monoclonal antibodies developed for administration to humans (for example, antibodies developed as ...

3. Rabbit hybridoma - Wikipedia

   en.wikipedia.org/wiki/Rabbit_hybridoma

   The rabbit formed a myeloma-like tumor, allowing the isolation of a plasmacytoma cell line, named 240E-1. Fusion of 240E-1 cells with rabbit lymphocytes produced hybridomas that secreted rabbit monoclonal antibodies in a consistent manner. [4] However, like the early mouse myeloma lines developed in the 1970s, stability was a concern.

4. Anti-thymocyte globulin - Wikipedia

   en.wikipedia.org/wiki/Anti-thymocyte_globulin

   Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors , which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency.

5. Monoclonal antibody therapy - Wikipedia

   en.wikipedia.org/wiki/Monoclonal_antibody_therapy

   Chimeric and humanized antibodies have generally replaced them in therapeutic antibody applications. [11] Understanding of proteomics has proven essential in identifying novel tumour targets. [citation needed] Initially, murine antibodies were obtained by hybridoma technology, for which Jerne, Köhler and Milstein received a Nobel prize.

6. Collagen hybridizing peptide - Wikipedia

   en.wikipedia.org/wiki/Collagen_Hybridizing_Peptide

   A fluorescence image of a sagittal section of an 18 d.p.c. mouse embryo double stained with biotinylated-CHP (detected by AlexaFluor647-streptavidin, orange) and an anti-collagen I antibody (detected by AlexaFluor555-labeled donkey anti-rabbit IgG H&L, cyan). mx, maxilla; md, mandibular bone; bp, basisphenoid bone; bo, basioccipital bone; vc ...

7. Nomenclature of monoclonal antibodies - Wikipedia

   en.wikipedia.org/wiki/Nomenclature_of_monoclonal...

   The nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to monoclonal antibodies.An antibody is a protein that is produced in B cells and used by the immune system of humans and other vertebrate animals to identify a specific foreign object like a bacterium or a virus.