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Amisulpride, sold under the brand names Solian and Barhemsys, is a medication used in the treatment of schizophrenia, acute psychotic episodes, depression, and nausea and vomiting. [ 9 ] [ 6 ] It is specifically used at lower doses intravenously to prevent and treat postoperative nausea and vomiting ; [ 9 ] at low doses by mouth to treat ...
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
In addition, due to their blockade of certain serotonin receptors, serotonergic neurotransmission is not facilitated in unwanted areas, which prevents the incidence of many side effects often associated with selective serotonin reuptake inhibitor (SSRI) antidepressants; [1] [3] hence, in part, the "specific serotonergic" label of NaSSAs. [2]
Both clozapine and quetiapine appear to bind just long enough to elicit antipsychotic effects but not long enough to induce extrapyramidal side effects and prolactin hypersecretion. [ 175 ] 5-HT 2A antagonism increases dopaminergic activity in the nigrostriatal pathway , leading to a lowered extrapyramidal side effect liability among the ...
Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used antidepressants in 2017, according to the ...
Its side effects include weight gain but there is lower risk for orthostatic hypotension and hyperprolactinemia. Aripiprazole binds D 2 as a partial agonist but antagonizes D 3. [20] In addition, aripiprazole treats schizophrenia, bipolar disorder (mania), [21] depression, [1] and tic disorders [20] Clozapine
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more extrapyramidal side effects (EPS) and less antihistaminic effects (e.g. sedation), alpha adrenergic antagonism (e.g. orthostatic hypotension), and anticholinergic effects (e.g. dry mouth) middle: perphenazine and loxapine: intermediate D2 affinity, with more off-target effects than high-potency agents low: chlorpromazine
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