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The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease. Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
The treatment of fecal impaction requires both the remedy of the impaction and treatment to prevent recurrences. Decreased motility of the colon results in dry, hard stools that in the case of fecal impaction become compacted into a large, hard mass of stool that cannot be expelled from the rectum. [citation needed]
Complications from constipation may include hemorrhoids, anal fissure or fecal impaction. [4] The normal frequency of bowel movements in adults is between three per day and three per week. [4] Babies often have three to four bowel movements per day while young children typically have two to three per day. [8] Constipation has many causes. [4]
Lilly's bowel disease drug gets US FDA nod for treatment in adults. October 26, 2023 at 6:46 PM (Reuters) -Eli Lilly and Co said on Thursday that the U.S. health regulator had approved its drug ...
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
Mesalamine is an anti-inflammatory medication used in the treatment of inflammatory bowel diseases. [68] In limited studies, patients with diverticulitis and symptomatic diverticular disease treated with mesalamine have shown improvement in both conditions. [69] Mesalazine may reduce recurrences in symptomatic uncomplicated diverticular disease ...
Additionally, fecalomas may be seen as masses in the colon. In the case of ulceration, the part of the colon adjacent to the fecaloma will be thickened. This thickening of the bowel will help differentiate from stercoral colitis and stercoral ulcer from fecal impaction as the colon is typically not thickened in cases of fecal impaction. [2]
Bowel ultrasound (US) is a cost-effective, well-tolerated, non-invasive and readily available tool for the management of patients with inflammatory bowel disease (IBD), including UC, in clinical practice. [79] Some studies demonstrated that bowel ultrasound is an accurate tool for assessing disease activity in people with ulcerative colitis.
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