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Having high levels of uric acid in the body can cause gout in the feet or other lower-body joints. However, not everyone with a high amount of uric acid develops gout.
Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]
Gout is due to persistently elevated levels of uric acid (urate) in the blood (hyperuricemia). [2] [5] This occurs from a combination of diet, other health problems, and genetic factors. [1] [2] At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout. [1]
Hypouricemia or hypouricaemia is a level of uric acid in blood serum that is below normal. In humans, the normal range of this blood component has a lower threshold set variously in the range of 2 mg/dL to 4 mg/dL, while the upper threshold is 530 μmol/L (6 mg/dL) for women and 619 μmol/L (7 mg/dL) for men. [1]
Gout is a painful form of arthritis that occurs when there is a buildup of uric acid in the body. ... potential blood pressure-lowering effects,” per the lead researcher, “as blood pressure ...
Throughout Drop Acid, Dr. Perlmutter offers suggestions and tips on maintaining lower uric values as well as a road map to addressing these hidden dangers. Per the description it also features ...
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