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Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder (OCD), and akathisia. [11] It is a long-acting [12] tranquilizer of the benzodiazepine class. [11]
Benzodiazepines have been shown to upregulate microglial spine engulfment and prompt overzealous eradication of synaptic connections. [180] This mechanism may help explain the increased risk of dementia associated with long-term benzodiazepine treatment. [181] The benzodiazepine class of drugs also interact with peripheral benzodiazepine receptors.
Clonazepam (1974). Clorazepate (1972). The following benzodiazepines are used to treat status epilepticus: Diazepam (1963). Can be given rectally by trained care-givers. Midazolam (N/A). Increasingly being used as an alternative to diazepam. This water-soluble drug is squirted into the side of the mouth but not swallowed.
Some packages of clonazepam were labeled with the incorrect dosage strength and National Drug Code (NDC), which is the FDA's identifier for drugs, according to Endo, Inc., the drug's manufacturer.
Clonazepam, in a class of medications called benzodiazepines, works by, "decreasing abnormal electrical activity in the brain," according to the U.S. National Library of Medicine.
Tablets of the drug clonazepam, the generic name for Klonopin, which is used to treat epilepsy, panic disorder and muscle spasms, have been recalled for incorrect labeling that could inadvertently ...
Finally, note that the benzodiazepine core is a privileged scaffold, which has been used to derive drugs with diverse activity that is not limited to the GABA A modulatory action of the classical benzodiazepines, [60] such as devazepide and tifluadom, however these have not been included in the list below. 2,3-benzodiazepines such as tofisopam ...
Cloniprazepam is a benzodiazepine derivative and a prodrug of clonazepam, 7-aminoclonazepam, and other metabolites. [ 1 ] [ 2 ] Some of the minor metabolites include 3-hydroxyclonazepam and 6-hydroxyclonazepam , 3-hydroxycloniprazepam and ketocloniprazepam with ketone group formed where 3-hydroxy group was.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261