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To prevent steroid-induced osteoporosis, the steroid dose and duration should be as low and as short as possible. All patients on long term glucocorticoids (≥3 months) should be encouraged to do weightbearing exercise, avoid smoking and excess alcohol and take fall prevention measures. Daily calcium and vitamin d intake should be sufficient.
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Steroid-induced osteoporosis: reduced bone density (osteoporosis, osteonecrosis, higher fracture risk, slower fracture repair) Weight gain due to increased visceral and truncal fat deposition (central obesity) and appetite stimulation; see corticosteroid-induced lipodystrophy
Since osteoporosis causes loss of bone mineral density, it makes bones more prone to breaking in the event of a hip injury. Hip Impingement Hip impingement is caused by a congenital abnormality.
Endocrine: By increasing the production of glucose from amino-acid breakdown and opposing the action of insulin, corticosteroids can cause hyperglycemia, [26] insulin resistance and diabetes mellitus. [27] Skeletal: Steroid-induced osteoporosis may be a side-effect of long-term corticosteroid use.
Prednisone is a type of steroid — not the kind that helps you bulk up your muscles but rather a corticosteroid. Corticosteroids are prescription medications used to treat inflammatory conditions.
Specifically, there are concerns that GLP-1 agonists may cause a loss of muscle mass and function. Such a loss of muscle mass and function is common in old age and is termed sarcopenia .
Steroid-induced osteoporosis (SIOP) arises due to use of glucocorticoids – analogous to Cushing's syndrome and involving mainly the axial skeleton. The synthetic glucocorticoid prescription drug prednisone is a main candidate after prolonged intake.