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Mesotrione is a selective herbicide used mainly in maize crops. [1] It is a synthetic compound inspired by the natural substance leptospermone found in the bottlebrush tree Callistemon citrinus . It inhibits the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD) [ 3 ] and is sold under brand names including Callisto and Tenacity.
In the mid-1980s, scientists at Stauffer Chemical Company published patents to benzoyl-substituted cyclohexanediones which led to their product mesotrione. [3] This encouraged workers at Rhône-Poulenc to expand their own research into molecules with the same mode of action as these 4-hydroxyphenylpyruvate dioxygenase inhibitors.
Mesotrione was introduced in 2002 and like sulcotrione is a triketone, so it is effective on the same weeds and crops, but is more potent, making it more useful in mixes with other herbicides - an important factor for fully controlling weeds and preventing the development of resistance. It has become the biggest selling member of the HPPD class ...
Leptospermone can be synthesized from phloroglucinol by a reaction with 3-methylbutanenitrile (isovaleronitrile) in the presence of a zinc chloride catalyst. . Phloroisovalerone imine is produced which is then alkylated with iodomethane after initial treatment with sodium ethoxide and methanol to produce an intermediate which is treated with aqueous hydrochloric acid resulting in ...
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Dimethyl tetrachloroterephthalate (DCPA, with the main trade name Dacthal) is an organic compound with the formula C 6 Cl 4 (CO 2 CH 3) 2.It is the dimethyl ester of tetrachloroterephthalic acid, used as a preemergent herbicide with the ISO common name chlorthal-dimethyl.
When you buy a bottle of vitamins from a nutrition store, you’ll probably notice a best-by date on the bottom of the jar. But that inscribed number isn’t a hard-and-fast rule—there is some ...
The therapy, branded as Ryoncil, is the first mesenchymal stromal cell therapy approved to treat pediatric patients aged two months and older whose GVHD symptoms have not responded to standard ...
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