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Several studies have now assessed the benefit of using preventive platelet transfusions in adults with dengue who have profound thrombocytopenia (platelet count < 20 x 10 9 /L. [17] There is no evidence that this reduce the risk of bleeding, but there is evidence that they increase the risk of harm due to the platelet transfusion (increased ...
Platelets collected by using apheresis at an American Red Cross donation center. Not all platelet transfusions use platelets collected by automated apheresis. The platelets can also be separated from donations of whole blood collected in a traditional blood donation, but there are several advantages to separating the platelets at the time of ...
Platelet transfusions are generally not recommended. [6] About 1 per 100,000 people are affected. [3] Onset is typically in adulthood and women are more often affected. [3] About 10% of cases begin in childhood. [3] The condition was first described by Eli Moschcowitz in 1924. [3] The underlying mechanism was determined in the 1980s and 1990s. [3]
Originally, platelets were stored in the donor’s own plasma. Nowadays, many blood banks have switched to using platelet additive solution to store platelets. Typically, when platelets are isolated from whole blood, not all plasma is removed, as platelets need to be in a certain volume of plasma in order to have a clear separation from other ...
Patient Blood Management is an approach that can be implemented in hospital settings for taking care of people who require blood transfusions. [4] PBM includes techniques that may help ensure each person receiving a blood transfusion receives optimal treatment for their condition and also ensures that the blood supply (bank of donated blood) is maintained to ensure that all people who require ...
Platelet transfusion is discouraged, as this too may aggravate thrombosis. [34] UK guidelines by the British Society for Haematology recommend the administration of intravenous immunoglobulin (IVIG) to reduce levels of the pathogenic antibody. [34] Low fibrinogen levels may require correction with fibrinogen concentrate or cryoprecipitate. [34]
Post-transfusion purpura is an extremely rare complication that occurs after blood product transfusion and is associated with the presence of antibodies in the patient's blood directed against both the donor's and recipient's platelets HPA (human platelet antigen).
Pancytopenia is a medical condition in which there is significant reduction in the number of almost all blood cells (red blood cells, white blood cells, platelets, monocytes, lymphocytes, etc.). If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.